Last year I started getting strange pauses in video playback on Youtube when resizing video or putting it in fullscreen and that can get a little annoying, especially when the glitch occurs at an important moment, I haven’t found out why this happens, only that it occurs due to the flash player being set to software rendering mode.
The easiest way to fix it is to download and use YousableTubeFix, it is a javascript file that adds certain enhancements to Youtube but more importantly lets you change the rendering mode, you will need the Gresemonkey plugin for Firefox but you can install it straight into Opera and Google Chrome.
The setting you need to change is the Flash Player wMode under All Pages after clicking the Configure button under any Youtube video and make sure it is set to Direct.
Once this is done a playing video should no longer have any pauses when resizing or fullscreening it. To verify that it is indeed working correctly you can right click the video and click ‘Show Video Info’, in the upper left corner of the video a little window should appear stating ‘accelerated video rendering’, if it is still showing software video rendering then it’s either not working or not possible with your hardware.